Abstract: This paper is concerned with the problem of computing the approximate -optimal design for polynomial regression with weight function on the design interval . It is shown that if is a rational function on and is close to zero, then the problem of constructing -optimal designs can be transformed into a differential equation problem leading us to a certain matrix including a finite number of auxiliary unknown constants, which can be approximated by a Taylor expansion. We provide a recursive algorithm to compute Taylor expansion of these constants. Moreover, the -optimal interior support points are the zeros of a polynomial which has coefficients that can be computed from a linear system.
Key words and phrases: Approximate D-optimal design, implicit function theorem, matrix, rational function, recursive algorithm, Taylor series, weighted polynomial regression.