Statistica Sinica 25 (2015), 225-241
Abstract: The Spatial Scan Statistic is one of the most important methods for detecting and monitoring spatial disease clusters. Usually it is assumed that disease cases follow a Poisson or Binomial distribution. In practice, however, case count datasets frequently present an excess of zeroes and/or overdispersion, resulting in the violation of those commonly used models, increasing type I error occurrence. This paper describes a modification of the Spatial Scan Statistic with the Zero Inflated Double Poisson (ZIDP) model to reduce type I error, accommodating simultaneously an excess of zeroes and overdispersion. The null and alternative model parameters are estimated by the Expectation-Maximization algorithm and the p-value is obtained through the Fast Double Bootstrap Test. An application is presented for Hanseniasis data in the Brazilian Amazon.
Key words and phrases: Double Poisson, EM-algorithm, overdispersion, spatial scan statistics, zero inflated.