Statistica Sinica 27 (2017), 1225-1242
Abstract: This paper considers Bayesian multiple testing under sparsity for poly-nomial-tailed distributions satisfying a monotone likelihood ratio property. Included in this class of distributions are the Student's t, the Pareto, and many other distributions. We prove some general asymptotic optimality results under fixed and random thresholding. As examples of these general results, we establish the Bayesian asymptotic optimality of several multiple testing procedures in the literature for appropriately chosen false discovery rate levels. We also show by simulation that the Benjamini-Hochberg procedure with a false discovery rate level different from the asymptotically optimal one can lead to high Bayes risk.
Key words and phrases: Asymptotic optimality, Benjamini-Hochberg procedure, false discovery rate, Pareto distribution, Student's t distribution.