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Statistica Sinica 13(2003), 423-442



A BAYESIAN APPROACH TO THE SELECTION AND

TESTING OF MIXTURE MODELS


Johannes Berkhof, Iven van Mechelen and Andrew Gelman


Catholic University Leuven, Free University Medical Center
and Columbia University


Abstract: An important aspect of mixture modeling is the selection of the number of mixture components. In this paper, we discuss the Bayes factor as a selection tool. The discussion will focus on two aspects: computation of the Bayes factor and prior sensitivity. For the computation, we propose a variant of Chib's estimator that accounts for the non-identifiability of the mixture components. To reduce the prior sensitivity of the Bayes factor, we propose to extend the model with a hyperprior. We further discuss the use of posterior predictive checks for examining the fit of the model. The ideas are illustrated by means of a psychiatric diagnosis example.



Key words and phrases: Bayes factor, non-identifiability, hyperprior, latent class model, posterior predictive check, prior sensitivity, psychiatric diagnosis.



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