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Statistica Sinica 12(2002), 61-86



PLAID MODELS FOR GENE EXPRESSION DATA


Laura Lazzeroni and Art Owen


Stanford University


Abstract: Motivated by genetic expression data, we introduce plaid models. These are a form of two-sided cluster analysis that allows clusters to overlap. Plaid models also incorporate additive two way ANOVA models within the two-sided clusters. Using these models we find interpretable structure in some yeast expression data, as well as in some nutrition data and some foreign exchange data.



Key words and phrases: Microarrays, SVD, transposable data, unsupervised learning.



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